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Bringing pharmaceutical products and services to market faster, more effectively, safely, and at a lower cost.

The LTS Biomedical Systems Division (BSD) is a newly-organized division that focuses on providing bioinformatics, integrative systems biology, clinical research informatics, and biomedical research Information Technology (IT) expertise to government, industry and academic clients. BSD assists our clients in bringing pharmaceutical products and services to market faster, more effectively, safely, and at a lower cost. We offer a full range of services from consulting to end-to-end project management and program delivery, including specialized data analysis, data management, and research IT support services.

BSD also has deep Portfolio Analysis (PA) and Research Management (RM) expertise, and offers a range of services from program evaluation to complete PA and RM systems re-engineering. This can include the provision of arms-length domain experts for program evaluation and to guide portfolio optimization strategies and tactics that can deliver measurable improvements in program productivity and impact.

Integrative Bioinformatics and Systems Biology Analysis Services

  • Next Generation Sequence (NGS) analysis, epigenomics, and transcriptomics data
  • Functional genomics, haplotype analysis, Copy Number Variation (CNV)
  • 1000 genome-like/population studies
  • Whole genome miRNA and siRNAs analysis
  • Proteomics and Metabolomics analysis
  • Pathway modeling and analysis
  • Tissue-specific measurements
  • Pharmacogenomics; Toxicogenomics
  • Imaging; Cognitive and Behavioral measures; Environmental measures
  • Integration with Electronic Health Record (EHR)-based phenotype data

Clinical and Translational Informatics Services

  • Clinical Trials Management
  • Clinical Research Data Management
  • Biostatistical Design and Analysis Services: Bayesian and Frequentist
  • Data de-identification, anonymization and IT Security
  • Integration with High-Throughput molecular and pathology laboratory measurements (translational bioinformatics)
  • Biospecimen repositories and databases (material and data)
  • Integration with certified Electronic Health Record (EHR) systems (structured and free text)
  • Guidance on Personalized Health Care company engagements and interfaces with IT environments

Biomedical Research Information Technology (IT) Services

  • Cloud computing and data services for bioinformatics and clinical research
  • Research data warehouse design and implementation
  • Turn-key normalized heterogeneous data integration and analysis solutions

Portfolio Analysis and Research Management Services

  • Rapid program and whole Portfolio Evaluation (with arms-length experts to analyze and measure the value of pharmaceutical products throughout the life cycle product development process )
  • Text-based Machine Learning (M-L) Classification of grants, contracts, and progress reports
  • Measurement of risk, reward, and researcher productivity against program goals
  • Network analysis for collaboration and research resource optimization
  • Workflow analysis and optimization

Application Domains:

LTS has a broad range of applications experience including all forms of biomedical informatics, systems biology, Infectious Disease, Bio-Defense, cancer, clinical research methods, neurobiology and mental health, and military medical and battlefield medicine. Biomedical IT, database development and query, and machine learning/automated classification is also core expertise within LTS BSD.

Original URL: http://www.ltscorporation.com/services/bsd.php